New Composites Collagen – Polyphenols as Potential Dressing for Wound Care
نویسندگان
چکیده
The aim of this study was to obtain new composites collagen-polyphenols and to investigate them as potential materials for wound dressings. Extracts from three plants: Arnica montana L., Artemisia absinthium L., and Urtica dioica L. were mixed in two different ratios and evaluated for their polyphenolic content and antioxidant activity. The herbal formulations were mixed with collagen type I and the obtained composite materials were chemically cross-linked with riboflavin. Their degree of cross-linking, enzymatic biodegradability, as well as their effect on fibroblasts growth and proliferation were comparatively assayed with non-crosslinked materials. The results demonstrated the potential of these porous composite materials for future application in wound care treatment.
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